DPCstruct | MC22469

Metacluster Properties and Pfam Annotations

Number of structural domains215
Mean domain length (aa)405 ± 98 aa
Standard deviation of domain lengths98.37
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score89.97
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)18.97
Pfam Score95.11
Assigned Pfam label(s) PF00408- CL0754

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A848Q975 6-296 AMISTGGEFTPTPAVSHAILVYNKGRTSGLADGIVITPSHNPPDNGGFKYNPSNGGPADSGITKWVENRANALLEGGLKEVRRMPYA…
A0A1I7XAQ4 177-597 SKVQEELMAKVANWLSWDKVCFIHYFIFLIPKKILYLIRFRFAQLAANVFISNGIPVYLFSDVSPTPLVSWATVALKCDAEDNGYKA…
M1VMA7 224-883 None
M1V875 122-708 None
A0A1V2LGQ6 43-525 None
U1PBB7 12-297 None
A0A1A9XGS3 759-1238 None
A0A7R9U9H7 147-690 None
A0A3E1K715 589-1011 None
A0A1A9X7A2 125-484 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.