DPCstruct | MC22464

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)130 ± 11 aa
Standard deviation of domain lengths10.75
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score74.49
Mean fraction of residues predicted as intrinsically disordered0.83
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)51.83
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J1W2D5 3-122 GNVRLWETSLDSLEKSLQEWRTMIGQEDGRPVQITIQRDSGLDVSSPKHGKIDPDNAPHVGGNTWAGGTGGRDTAGLGGKGGPYRLD…
A0A1I7X5Y5 1-148 MLTLDTCGGIRSFELSLAGLSTSFSEWKKMIGGNDSVPLRLEIDRKPDDFDIKKLDEPKIGKFDPSNAPHHGGNTWMGGTGGYNTAG…
A0A6I9YHN7 3-129 None
A0A3M7S582 108-240 None
A0A7S2S540 452-579 None
A0A5N5SPY1 491-619 None
A0A2I0TLY6 165-291 None
A0A7S4QQ91 45-179 None
A0A5E4CMB8 661-787 None
Q19346 1394-1527 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.