DPCstruct | MC22463

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)90 ± 9 aa
Standard deviation of domain lengths8.60
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score86.16
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)35.53
Pfam Score78.03
Assigned Pfam label(s) CL0016- CL0001- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7HWS0 32-113 VSVRVFYKTCPLTVRNLATFPDTVTGADTSSLVEVRGSCVNQSEEREEPKMYCGADGEWLVPIGGCLCRSGYEEQGGACKAC
A0A1I7X341 49-134 SFKVYYVVCDASTTRFTQYPATVTSSVREDMVKVSGKCVRNAIASQSEPPTGFCTSSGRWNHLIGECACKPGYMGQDIKGEQSCHV
A0A0D6MBT0 12-108 None
A0A4Z2FR39 348-444 None
A0A2R7VSL6 63-142 None
A0A132AF98 86-171 None
A0A402FGY3 333-414 None
A0A498M3X2 331-417 None
S4R4K2 132-228 None
A0A5B7FJ21 16-109 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.