DPCstruct | MC2246

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)693 ± 79 aa
Standard deviation of domain lengths78.59
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score68.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P4ZQZ0 9-701 GRLHLNWEADSFNLFRQPSKGENWNPDLLRYCVGILKELLLAMKELNMLGGCCKSFPIFIKRDSSNRVTAADVIFESVWQFVQLLSE…
A0A093ZG47 266-988 RIEDVKRLLDERFSSVAKEDFIWLRELREHGYETEEIAQLLLTEQNDSPWIYFEPRDLPREAIIPDHHEAFCVHKGGQEVRHEIKSI…
A0A179FQF4 336-1055 None
A0A178BJ81 510-1186 None
A0A370U1V4 42-870 None
A0A1V6TZR6 196-839 None
A0A4S9MVC9 443-1138 None
A0A1V6RGG4 7-632 None
A0A2S7QSN9 1-833 None
A0A2J6PF31 231-981 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.