DPCstruct | MC22452

Metacluster Properties and Pfam Annotations

Number of structural domains508
Mean domain length (aa)153 ± 30 aa
Standard deviation of domain lengths29.92
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.44
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.95
Pfam Score97.11
Assigned Pfam label(s) CL0496- CL0128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A257QLQ8 10-172 None
A0A0A0EAV1 11-175 None
A0A2V7PNV8 3-102 None
A0A7Y2IIE8 1-162 None
A0A377J9Q5 4-168 None
A0A536B8C2 2-181 None
A0A448TVC1 10-191 None
A0A536AKT6 1-166 None
A0A537WVK9 99-249 None
A0A3S1FYD1 12-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.