DPCstruct | MC22452

Metacluster Properties and Pfam Annotations

Number of structural domains508
Mean domain length (aa)153 ± 30 aa
Standard deviation of domain lengths29.92
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.44
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.95
Pfam Score97.11
Assigned Pfam label(s) CL0496- CL0128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W6E0G7 47-188 RGGRRPGAGQRGSMSVELVVIAPGLIGLLLLVGAGGRVVEAQGHLDGAARDAARAASLAISPAQASQLALQAAQADLGTTSWCAARS…
W5XXK7 2-93 AAVFVAAFVSLAGVAVYAAAGVIGIHRAQVAADMASVSAAHEHYVGGDGCAEAAEVIRLNGADLSDCFVEGMDVVVRAEMAGGDAVA…
A0A2E4QQZ4 9-181 None
A0A534W5R5 3-148 None
A0A0M4KJQ0 14-179 None
A0A0G3XH86 6-150 None
A0A7K3WAR9 1-171 None
A0A1X7NRP6 3-148 None
A0A3R6X018 13-158 None
A0A418WTK6 4-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.