DPCstruct | MC22421

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)77 ± 6 aa
Standard deviation of domain lengths5.71
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score85.83
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)49.28
Pfam Score100.00
Assigned Pfam label(s) CL0093

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3ANE5 231-310 EPPDPMLLKNAFESKDLYFYCGHGDGGRYLSGEELQRLPRCPATVLMGCSSGVLKQQGRLPPCGMALNYLHARCPALVAN
A0A835IDS7 1-86 MAQGKAETPSVEELVLALKSHDLFLYFGHGNGTQFLPKYEIEKISSCAATLLMGCSSGSLPFVGCYNPHGIVLSYLLAGSPAIIAN
A0A395IMX8 287-361 None
A0A7J7MIA0 295-365 None
M4B6W9 138-217 None
W2YV04 70-149 None
P18296 1684-1754 None
A5C0X5 459-540 None
A0A6V7P8I8 229-297 None
A0A0D2LSY6 433-510 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.