DPCstruct | MC22406

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)111 ± 13 aa
Standard deviation of domain lengths13.21
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score78.06
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)46.43
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835HTE1 92-207 FDRQQLLKNRIDDHLSLPVGCPQDFEFQNYTIITSQCKGPQYPPTLCCDAFKRFACPYAAYINDLASECAYVMFSYINLYGKYPPGL…
A0A5J5NKZ8 4-92 ASTSISACPIEFEFLNYTIITSECKGPKYPANRCCAAFKKFACPYAKQINDLTTDCASTMFSYINLYGKYPPGLFAAECREGKRGLK…
A0A7N0RE90 60-176 None
A0A2I0HK41 6-111 None
A0A4S4D6U9 842-965 None
A0A835J258 319-443 None
A0A2K1IYE1 7-133 None
M4CF58 1-77 None
A0A0E0JIC4 43-148 None
A0A830CNV5 25-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.