DPCstruct | MC224

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)108 ± 17 aa
Standard deviation of domain lengths17.32
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score73.15
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)37.52
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K3WJ08 1-84 MRLARRPCVKIQYRDDALRAHFCKNAQQLLDFVQTDPNNKTMSALIARKALQYRHVRIDRIGDIDVRDPTFDVSHFFDIEWSKV
T0Q1X5 10-93 QESHGCAARRHYQLSYSDDAVKQRYDHIVRTTLRLANSPDVNSKNVLLAQKAIKYRRHESDAINYDDPSTDVFESLGITWCKTP
A0A3F2RQB4 1-109 None
K3WJH1 1-115 None
W3A9X0 114-210 None
A0A5D6XEP2 53-186 None
A0A662XEM6 41-157 None
A0A5D6Y8J5 117-262 None
A0A2D4CGQ1 119-207 None
A0A0W8D389 49-170 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.