DPCstruct | MC22398

Metacluster Properties and Pfam Annotations

Number of structural domains1150
Mean domain length (aa)126 ± 25 aa
Standard deviation of domain lengths24.69
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.62
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.11
Pfam Score92.77
Assigned Pfam label(s) CL0084- PF07335- CL0029- CL0229- CL0209

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A1ZZ88 570-675 None
A0A4Y7TV11 12-146 None
A0A7I4EJY8 277-394 None
A0A834TVV0 3-114 None
A0A537TYA8 2-82 None
A0A6G1HT02 74-211 None
A0A396QBK1 307-406 None
C7N3Z3 240-369 None
A0A146HMM1 33-152 None
A0A164QS35 644-777 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.