DPCstruct | MC22398

Metacluster Properties and Pfam Annotations

Number of structural domains1150
Mean domain length (aa)126 ± 25 aa
Standard deviation of domain lengths24.69
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.62
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.11
Pfam Score92.77
Assigned Pfam label(s) CL0084- PF07335- CL0029- CL0229- CL0209

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3N1HVN8 4-163 SDLLAKVTSCSQISNGKYKTDDETSATVPVCGKNGAVFWKADMDIDCDGQRTTNCNEDRDPWYQDDTAFHQSDGKPLKAESLPYVVV…
A0A2V7EC41 11-127 CATPGVVRTPAPSLLGTEWTGLASWYGDPHHGRETASGEVFDKTKPTAAHRALPFGTRLAVTNLDNGRTVEVRVNDRGPFVNGRIID…
A0A4Q6FZD0 12-151 None
A0A261DCZ3 61-165 None
A0A7S1UP23 159-309 None
A0A5P1F3W9 10-124 None
A0A4S4DPH8 41-183 None
A0A4S4DHT8 199-274 None
A0A387HSC3 138-263 None
A0A519T6I8 33-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.