DPCstruct | MC22390

Metacluster Properties and Pfam Annotations

Number of structural domains127
Mean domain length (aa)196 ± 45 aa
Standard deviation of domain lengths45.13
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.81
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)15.17
Pfam Score80.48
Assigned Pfam label(s) PF03799- CL0191

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A358GWD4 6-154 VDRVVVSRAWPNGIRVRVMPRHAIARWGTGRLLSDGGDVFSEAEPTIHPELPLLHGPVSQSKMMMRRYNEINQLFHPANLRLKELYL…
A0A7C5F8D2 27-232 LQIRQIGVKGNIKITTEEIQGRLGSFMGENLLLIDENEVQAKMSSDKRINQIEIKRKWPSTLLIQLTEKKPVLLLDYSQMWGLSPEG…
A0A2D8N254 27-286 None
R6QZ48 2-187 None
A0A3S0PDT6 28-270 None
A0A7V1I4I6 1-100 None
R5Z4W7 19-214 None
A0A1G1DIV5 48-285 None
A0A2G9X302 18-204 None
A0A520T0C4 33-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.