DPCstruct | MC22381

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)94 ± 13 aa
Standard deviation of domain lengths13.06
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score86.51
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)28.16
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y4ZIQ4 6-102 RAEIAAMVAEGLAGADDVVQRAWARLAMPPAEWECEGAPDGERFWVVGRIAAEIVWYNHIEEGFNRSPCRSERVIGEYRCNQSTFAE…
A0A8B2NJ48 3-93 RAIDALSLPERQFWEAIKVEPQKWRCPPWGDAGGGFWVVGLFGQYVIWYNDIEDGFNCSRYTTRGTIGEYTCDQNELQYTVRSLKVL…
H1Z9Y7 16-101 None
A0A699GFB8 923-1013 None
A0A7X3FWR5 2-98 None
A0A7S9L0U1 15-108 None
A0A177LKK8 3-73 None
A0A7X7DR65 12-121 None
A0A654CMV1 3-63 None
A0A3D9KBP0 183-287 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.