DPCstruct | MC22378

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)84 ± 9 aa
Standard deviation of domain lengths9.44
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score96.11
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)53.15
Pfam Score100.00
Assigned Pfam label(s) CL0061

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X3C4T5 71-158 IYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRLIDGSIERSIKFRKEIKRLKGES
A0A4U9WQ52 2-85 IYETQSTHKLLAAFSQASMIHVKGDINEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRMINGSIERAIKFRKEIKRL
A0A2X3CCV0 55-143 None
A0A7K4BFA5 184-265 None
A0A485BEQ5 1-73 None
A0A6F9EIC1 65-146 None
A0A4U9U313 19-107 None
A0A4U9HKE6 38-120 None
A0A7I8CHL0 3-114 None
A0A376RDA2 92-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.