DPCstruct | MC22370

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)94 ± 6 aa
Standard deviation of domain lengths6.11
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score90.16
Mean fraction of residues predicted as intrinsically disordered0.57
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)43.79
Pfam Score100.00
Assigned Pfam label(s) PF00696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0B8QDT3 29-119 DENDPAIANPTKFIGPVYAEEEAKQLAEQNNWIVKPDGAYWRRVVPSPTPKEVLEIKAIQDLLEKEHLIICGGGGGAPVVEKDGAYY…
A0A4U9WET9 1-98 MDKQDPGFTNPTKPIGAFFSEQQRDALLQQYPTWRFVEDSGRGYRRVVASPEPIRIVEADAIKALTQQGFVVIGAGGGGIPVARNSQ…
R6Z1Q8 20-113 None
A0A255PAF6 89-182 None
W7C657 218-310 None
A0A841DL44 274-365 None
A0A2V7IFY8 944-1047 None
W9T803 111-202 None
A0A813D975 8-104 None
A0A5C8JDR8 114-206 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.