DPCstruct | MC2237

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)252 ± 16 aa
Standard deviation of domain lengths15.94
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score89.30
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.25
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J5TXP2 6-231 RLESFRTPKTYVTVVYWLIGGLVLGLLLVRPGAWWTPALAWVYVVLAWLYFNWRYSPVVQFPVLHTAHNVVGRWAATTDRPESVRKL…
A0A5C9EKC1 1-281 MVEMMHKEFTELMGRWCIPRLVGSEGSHKIVKLLKQDFDRFNFECEEQEFPVFKSDTSFKLSRKLAIIGVLSSIFLILFWILFLYSL…
A0A416ZFC4 4-265 None
A0A2N3F8N1 6-239 None
A0A0F9Q9E5 8-263 None
A0A532TKI4 1-263 None
N2C0A4 10-262 None
A0A538EXN0 2-234 None
A0A437UTR6 6-242 None
A0A1F8QE10 17-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.