DPCstruct | MC22367

Metacluster Properties and Pfam Annotations

Number of structural domains3
Mean domain length (aa)87 ± 9 aa
Standard deviation of domain lengths9.20
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score84.42
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)54.35
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9W6T7 1-80 MVLMDLGSALLSAETALELLDPEVAAKVVLCAAPLVEGTLAAVVAANAGASLEQVLAEAQGALQAKQAQLGEAIPASKPL
A0A378A5B9 280-360 VLVMMDIGSALLSAETALDLLDPAIAAKVRLCAAPLVEGTLAATVSAASGAGIDKVIADAMSALEAKRVQLGLPSPTSDAA
A0A212IVC5 55-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.