DPCstruct | MC22365

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)283 ± 29 aa
Standard deviation of domain lengths28.62
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.44
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F2K781 71-341 VQPKCRVEGESAILALQRGDYLQAFDQLYRGQSNYWYDAAAVAERVLTVDELKQYVDAQVPAPPALSQEDRDNYVPLPVAASLRNLL…
R4YHD4 6-256 QAKENYWPDVAHIAERVLTVNELLAFVDKYVPAPSPLAPTTPKNAGRDSADARLRNLLARRLMRAGQYQKALAYFALAEDRDAARAF…
A0A7W7YEH0 444-746 None
G1Y2T2 227-553 None
A0A2V5W796 868-1130 None
A0A3S5AF68 1-281 None
A0A178MCX1 718-947 None
A0A433SAH5 433-740 None
D4E097 322-607 None
A0A809SDD2 32-343 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.