DPCstruct | MC22350

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)83 ± 5 aa
Standard deviation of domain lengths5.39
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score79.28
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)33.18
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2M7PX76 10-86 ISDHNAMRSLIGRPVRYADEACEICDVLFEESLLVLASLSCDEMQDDSYGRPHRKVPAYHSLPFKDDAGNPSYMWGE
A0A1I1P1E8 18-101 DDNEKQARDLLGRTVDYRGRTCRVVELLDDPPALILQDEGSGTEMQANQHGEAHRRVPRNYTVALYHYNAAGEREVHPDFRALQ
A0A6N4E268 8-86 None
A0A7C1CY55 6-90 None
A0A6I7N4M7 11-101 None
A0A7C5XSZ5 9-94 None
A0A7C3D0R9 2-84 None
Q3J7A9 25-115 None
A0A363UKA3 3-76 None
A0A317MRK9 5-89 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.