DPCstruct | MC22328

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)157 ± 37 aa
Standard deviation of domain lengths37.38
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score79.51
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)26.36
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2RRB7 7-140 ACLPSRQDVTRNFIYFRRFQKHTISRSAVLVYNQIVPFWEKSRLLVRDKQHVLKQIKDLYGKQENLMKQRKRNNAKDQENQKIYCNN…
A0A4Y2AXI4 3-109 LSLRESARLVISETVIFWKKARIPFREFQHCIVKLEALYNEWRMLQKHSKRKSETQEQKEQNFKQKLEDLLDIAHSNALIIITIEED…
A0A4Y2A874 5-163 None
A0A7T8K0X4 2-104 None
T1EUQ1 1-200 None
A0A834Y124 1-139 None
A0A4Y2CCZ9 2-212 None
A0A4C1U6C0 15-144 None
A0A4C1UTG1 30-160 None
A0A4Y2A693 3-225 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.