DPCstruct | MC22299

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)235 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.49
Mean fraction of residues predicted as intrinsically disordered0.71
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)25.38
Pfam Score73.61
Assigned Pfam label(s) PF08703- PF06631

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183CHZ7 1-284 MFVWFSLFLHPSARPFDIFQQQVEWINIADLRREKLFLKLQKKLAKEWVEMKNKHQKSRENVQKQQQSSVDRLVKRNHLNSTSLGER…
A0A7M3Q8N2 1-239 MLRNDKNYRKLVKKQAKDLEMLRRRHEKEASTMLRAHTILTDKLNAAHAKASSGHRGAPQKSNGVNSPLKDLHKSEMSDLVRQQTDQ…
A0A2D4EQ40 348-606 None
A0A814SK86 2-217 None
A0A182F5F7 907-1158 None
A0A5N4D7V5 22-249 None
A0A833RH39 63-293 None
A0A4Y2IX25 220-400 None
A0A0N4UYD6 704-962 None
A0A811L8N9 2-226 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.