DPCstruct | MC22298

Metacluster Properties and Pfam Annotations

Number of structural domains81
Mean domain length (aa)104 ± 20 aa
Standard deviation of domain lengths19.87
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.44
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)33.31
Pfam Score99.11
Assigned Pfam label(s) PF04502- CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183CHB6 13-109 YPPDFDPAKIPKAKQPRNRQFIQRVMTPFNMRCNTCNEYIYKGKKFNMRRETAEGESYLGLKIFRFYFRCPNCLAEITFKTDIENVD…
A0A0C2TNB4 11-106 FPPDFDPDLIPRRKQPKNSQQVVRLMAPFSMRCNTCGEYIYKGKKFNARKETVDGEDYYGIKIFRFYIKCTLCSAEITFKTDPKNTD…
A0A5D2VQD8 3-86 None
A0A6D2HK97 75-164 None
A0A0C2IS38 16-135 None
A0A6A5WRW5 140-269 None
M9LVZ6 16-112 None
A0A094I2L7 15-108 None
A0A139WAV5 19-135 None
A0A6A2XRA6 1-82 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.