DPCstruct | MC22293

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)148 ± 15 aa
Standard deviation of domain lengths14.88
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score76.06
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)32.60
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5M9JWY9 14-163 NNKSKEYWRTALYIPYLTFSTYSETGAELTKSGKKVEKLLKAYGIQNKNDNEDSDMATGNDSRRIIHSSRTLDQFYYHSLKDTKSRD…
U7PS92 621-755 KVVLFMPFLHYETDERRQRMTHAINLVRDGWDPPVGSPRDIMLTKGYLCNTPPLHPRRTLDQFFYHGIDTSIRDTDQVVYRYCKRHN…
A0A6A6RDQ6 143-292 None
A0A2B7XIH8 154-270 None
A0A4S3JW33 60-230 None
A0A2J6TFB5 146-296 None
A0A2J6TG17 38-202 None
A0A2V1BFL1 7-156 None
A0A7C8ML03 1-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.