DPCstruct | MC22291

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)233 ± 38 aa
Standard deviation of domain lengths38.46
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score75.88
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)33.88
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A367JJV2 128-387 MQPIAYHIYFSSSQYVSDHEKVSIALYVSAGYLVLIFIGSWYLYHNRTLVNRATLQQQTVLKVLLFILFELILFPTLCGFFLDLSTL…
A0A444T935 329-511 LCGYCVVGIVLVILHAFAALIKLNRSKRVLGLCYIVVKVALLSVVEIGVFPLVGGWWLDICSLSLFDVTLKDRETSFNIAPGTSMFI…
A0A0F4YSW3 546-785 None
K3WHR2 31-234 None
A0A7M7GFY8 363-623 None
A0A836D968 50-224 None
U7PSI9 1213-1446 None
G0S8R7 430-654 None
A0A3B6KQN6 125-362 None
A0A0B2VJ42 30-349 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.