DPCstruct | MC22285

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)211 ± 18 aa
Standard deviation of domain lengths18.08
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score86.28
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)20.58
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0WT23 217-391 PDSIVDLAASLARDKKVFMDPVFAASLVDDFAVAGHVKAACDLFRLVPNVWLSLCPHLPIALINDPSGHKTGYIYRIFEMLNRDDPT…
A0A5M9JLY5 95-302 REFDQIDAVLKQSRMFNLPVNSSILADLVNNMASVNLHAAYDIYMRYCLGNVEPEACAPLIASMIYKRGSKRIWAAFDAPIYAAMPR…
A0A2C5XIC9 329-528 None
A0A177A8T6 1-219 None
A0A6A5VIQ0 2-253 None
N1J7C5 398-624 None
A0A842Z555 5-215 None
A0A2S7P321 1-196 None
A0A6G1L315 494-696 None
C7YKR8 121-342 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.