DPCstruct | MC22281

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)204 ± 30 aa
Standard deviation of domain lengths29.97
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score65.64
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)39.41
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B2WMN5 1-208 MSTVFSSLVRPPKIRSPSTNTQEATSSLASISNYGVEEPDLRDLNAALQALTDIFPNIQPEVFREMLSTFSEESRLQVVTETLLKHG…
A0A428QQZ4 1-137 MVFPGLLSSSDRTPSTRGDPDPEYIYDEAQLATAPPERPDLRELNASLEALAAAFPDVQVEVFRELLRNFDGESRLALVADALLKNR…
A0A4U0VEM5 1-179 None
A0A395J6Z2 1-224 None
A0A094HG85 1-200 None
A0A1L9UYR9 248-480 None
A0A5M8Q0E8 1-225 None
A0A4Z1KSS3 1-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.