DPCstruct | MC22278

Metacluster Properties and Pfam Annotations

Number of structural domains318
Mean domain length (aa)270 ± 60 aa
Standard deviation of domain lengths60.16
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.17
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.10
Pfam Score81.31
Assigned Pfam label(s) PF00940- CL0194- PF00067- CL0219- PF00476

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A820QQ83 22-206 None
A0A378W386 2-236 None
E4UE10 413-715 None
A0A4W3GV56 15-175 None
G0R152 58-261 None
A0A1I7V638 793-1078 None
A0A7M6DNX6 3-313 None
A0A813EZ91 826-1094 None
A0A383WQ56 48-331 None
A0A830HFH7 807-1138 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.