DPCstruct | MC22278

Metacluster Properties and Pfam Annotations

Number of structural domains318
Mean domain length (aa)270 ± 60 aa
Standard deviation of domain lengths60.16
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.17
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.10
Pfam Score81.31
Assigned Pfam label(s) PF00940- CL0194- PF00067- CL0219- PF00476

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2Z451 3-154 None
A0A2E6JFE4 3-150 None
A0A0F9TX64 333-574 None
A0A0F9TTR6 263-479 None
A0A485MPQ9 488-778 None
A0A836CN43 29-319 None
A0A836CFM6 32-279 None
A0A836C9D4 27-284 None
A0A4Y7NN91 375-701 None
A0A835ZFH7 52-311 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.