DPCstruct | MC22278

Metacluster Properties and Pfam Annotations

Number of structural domains318
Mean domain length (aa)270 ± 60 aa
Standard deviation of domain lengths60.16
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.17
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.10
Pfam Score81.31
Assigned Pfam label(s) PF00940- CL0194- PF00067- CL0219- PF00476

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A2LQQ5 399-922 None
A0A3M2RJT2 238-461 None
A0A7C1VVZ6 7-249 None
A0A800EH13 83-430 None
A0A2I2KVF6 10-237 None
M2XLB5 742-1045 None
A0A1Z9LY72 173-407 None
A0A5D4GZH4 299-516 None
A0A502GD82 593-929 None
A0A3C0G7B8 33-278 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.