DPCstruct | MC22278

Metacluster Properties and Pfam Annotations

Number of structural domains318
Mean domain length (aa)270 ± 60 aa
Standard deviation of domain lengths60.16
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.17
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.10
Pfam Score81.31
Assigned Pfam label(s) PF00940- CL0194- PF00067- CL0219- PF00476

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A349NCK7 2-286 KTFVISDLSQIEPRLTAFVAGDTAFLDLIGQGMSPYEAHARQTMGWTGGKLKDEDPELYLLAKVRVLQLGYGSGWFKFAETVKQYGQ…
A0A6P0JW15 34-310 ISTFTEGLPTHIHPVTGRMHPDWFQIGARSGRFRCRHPNLQNIPRDKATRSCFTAGEGQVLIKADYSQVELRIMAKVSGDKRMKRAY…
A0A202DFW1 6-171 None
A0A0F9U4M4 657-868 None
A0A1X7U0L7 378-713 None
A0A061QUT7 23-300 None
A0A378N190 14-191 None
A0A1Y5S0I5 4-199 None
A0A0G0BAJ1 22-251 None
A0A1G5FBH8 3-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.