DPCstruct | MC22269

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)168 ± 23 aa
Standard deviation of domain lengths23.10
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score79.56
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)30.48
Pfam Score100.00
Assigned Pfam label(s) PF10158

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H1VTH7 10-143 EIPTFLPIMRGTLGLPGARDPEVLEGLDYRPWVRVTTRLQAHLAACAHPLATIEGGLAAKIKEADQEISRLYSQMVDKQRANARHAE…
T1J5R9 70-228 GHDIVVVQEANQPEESTENDSELCRLQVIPTFLPIMRGALNIPTMTDVDVLDKLDHGSILNVCSRYQEHLKQCSEVVSTEQNTLATR…
A0A5N4A327 211-376 None
A0A0C9RQH4 101-257 None
A0A0N5D890 1-184 None
A0A0N4WBL7 5-194 None
A0A0N5AK77 34-190 None
A0A6J0INW9 10-187 None
A0A132A261 11-204 None
L8YDJ3 7-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.