DPCstruct | MC22265

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)141 ± 19 aa
Standard deviation of domain lengths19.44
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score66.19
Mean fraction of residues predicted as intrinsically disordered0.88
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)43.05
Pfam Score100.00
Assigned Pfam label(s) CL0680

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1IUK9 7-150 EIHEQKGNHVLHIRGDSDSDLEALFKSVINPTDTQVSLIVPMRLRKLPKSFFKPPETGSRTPPQQTSTSSRSGLPASGGTTTGLQIH…
H2Z0P3 10-126 ITQGHNQIIHVRQDSASELEALFNTVMNPNFKSKSLPMKARNLPKSFFTQPDKPRQTSMYHHGHSHNFHFRSKSSPASLQLMDVGNL…
T1HC02 4-155 None
A0A4U1ETI9 42-192 None
A0A6P3YIV1 5-144 None
V4BET5 1-145 None
A0A195CJ14 1-193 None
A0A818WZ62 1-121 None
A0A6I9Z0Y7 37-181 None
A0A2G8L677 1-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.