DPCstruct | MC22250

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)111 ± 17 aa
Standard deviation of domain lengths17.31
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score92.85
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)39.97
Pfam Score100.00
Assigned Pfam label(s) CL0339

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R6KS31 146-256 EILKSRLILAKESLLHRYGILKKLRVKDLPFVAGQKLMKGAENLEEEDSIEPILRQGTWGIGFIGLAEALTALIGKHHGENDEAREL…
J9FRL8 3-103 RHERLSGTLSDAAPILWQYGALARLPKGETIDKLLHSGYSTISLGFAGLYECVRYMTGHSHTDAEATDFALAVMQHMNDKCAEWKAK…
A0A091C7Y5 12-113 None
A0A090S659 330-443 None
A0A496KAP7 2-112 None
A0A7C7DS11 7-132 None
A0A7X7NW09 1-141 None
A0A2X2T2B5 8-87 None
A0A0A2W4U6 732-843 None
A0A4U9TPX1 103-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.