DPCstruct | MC22248

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)79 ± 4 aa
Standard deviation of domain lengths3.56
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score92.98
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.95
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)47.63
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A447NW45 3-79 GDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEDYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKTHI
A0A7R6KJZ6 32-109 ENEERNIVLTLARIWYSTETGGIVPKDVAAEWVLERLPAEHKPILVEARQAYLGLCKDSLALRADETSAFIGYAKSAV
A0A7I0PN22 341-417 None
A0A5Q2NBB7 136-212 None
D5SKZ3 274-358 None
A0A7W0ZCI9 1-87 None
A0A6I6HG79 180-257 None
A0A699JJX7 253-330 None
A0A1P8YVW4 114-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.