DPCstruct | MC22205

Metacluster Properties and Pfam Annotations

Number of structural domains97
Mean domain length (aa)148 ± 32 aa
Standard deviation of domain lengths31.66
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score91.18
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)20.98
Pfam Score77.49
Assigned Pfam label(s) PF01977- PF20696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X3F4G8 11-149 YKNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQ…
A0A4R5NDZ9 327-483 EHVSMAGIPTEASILELVDKAIPGKVVNVYNPPAGGGKLMTIMQIHKDNEADEGIQRQAAILALSAFKELKTVFLVDEDVDIFDMND…
A0A1B0C782 323-471 None
A0A133UX92 18-170 None
A0A167NXY0 307-483 None
A0A7C1BK74 1-110 None
A0A1V5C7V3 2-93 None
A0A3S4JVF7 129-289 None
A0A5V4GKA9 512-667 None
A0A377LUH1 6-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.