DPCstruct | MC222

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)311 ± 33 aa
Standard deviation of domain lengths32.94
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score81.94
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)24.34
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A662WHG7 397-687 SIESRSPDDQSALFRRVQQLEKQLQQAGIVVAADISYDEALAKVQAIALRMGEIGSSDVEHPDPAIQKQLREEYYLMEQEMEKFNAA…
T0PY92 99-379 VPLPVSTPRNDPVMDRLVAIMRPNDSYDELTRRIQEISRRMRAIGTADVTHPDPLVQRDLREEYFVLEQDMEACHDAIQHKPEYAIE…
A0A6G0XUI4 17-302 None
A0A1V9YLG4 75-449 None
A0A7S3PG07 1-280 None
M4C6T0 10-301 None
A0A7S0UMQ6 130-509 None
A0A482S9B9 236-568 None
D7FM20 5-277 None
A0A7S4E5B8 67-349 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.