DPCstruct | MC2217

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)126 ± 14 aa
Standard deviation of domain lengths13.61
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.83
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)19.12
Pfam Score100.00
Assigned Pfam label(s) PF07205

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W8T8Q6 15-129 FMDNKSVQILFTDKQYQDLEKKAAKAGLTVPLYIKGIVLENDEFSLAYAKLIKKVDALPSGTRFTIRSLFGTEWTMGRGIKLSLGKT…
F3ZXE5 1-127 MRITIDFDDEFSETIKRESIKNGISLSEFIKRCVQRCINDGIVFKEVENYVDDETIQKILEESLDKLPSKKKFLLQELFGLDWRDLT…
Q2VHL1 1-114 None
A0A1M6P231 1-149 None
A0A374AVP6 35-151 None
A0A1E7W6A1 63-187 None
A0A839HL86 1-133 None
A0A520GGC1 1-133 None
D5Q9Z8 7-98 None
A0A0Z8HEC1 1-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.