DPCstruct | MC22154

Metacluster Properties and Pfam Annotations

Number of structural domains132
Mean domain length (aa)107 ± 11 aa
Standard deviation of domain lengths11.42
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.42
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)29.42
Pfam Score98.61
Assigned Pfam label(s) CL0056- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A556V9Z2 24-130 SQIEVYPKHGSVSGVFHAGLSGVYAFNASVAREVCERLGVAMADKPQVEKALALGLQTCRFGWIDEQVVVIPRIQAKASCGQGGLGI…
L5L6F4 6-115 LEGVVFPYHPRGGRYKLTFTEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVSQPREPCGGAGSAGVGEGANGGV…
A0A4W6EB47 84-215 None
A0A6C0JEK5 300-410 None
A0A3Q1GHL4 19-117 None
H0ZCB4 14-119 None
A0A2E4IFF8 57-171 None
A0A1S3IKE4 32-135 None
A0A4Z2ED34 82-182 None
A0A1S3ID39 169-275 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.