DPCstruct | MC22151

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)211 ± 43 aa
Standard deviation of domain lengths43.03
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score81.49
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)35.25
Pfam Score69.05
Assigned Pfam label(s) PF08165- CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J1VXI3 39-252 EIDDGLGFLPTFGPCYVNLYGSPREFTGFPDPYEELNSGKGEGVAYRGRLLVELETKLVDHVEQKLGDIPADDILRVEKYLRRRKYN…
A0A3S5CUT5 1-102 MRRRKYLLHCAFHSATLIGETDGPVEFEVSIGNYGNKLDGSVKPSSSTTQPTNAVYDGTYYHFLPWSESKPCTVVESHWEDISYRLG…
A0A6A5DFM3 5-175 None
A0A817HM92 41-264 None
G3NZL8 465-740 None
A0A3M0LFF1 910-1126 None
A0A1S3ID79 133-387 None
A0A5E4BWA6 102-309 None
A0A6S7HPN9 1-228 None
A0A2B4S5W7 195-308 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.