DPCstruct | MC22109

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)483 ± 32 aa
Standard deviation of domain lengths32.20
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score89.27
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)37.82
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W2CK26 42-519 PQAMFPPLSLVDGGRVPAQVMLGVVAQESNLWQASRLAYPGVTGNPLIGNFYGLIYNDREDDDWTIRWSEADCGYGVAQVTDGMRRA…
A0A1Q4YBH7 12-499 AQGLFPPTALDGGGHVPAQVLLGIATQESNTWQAAKFAVPGMTANPLIGNYFGIDYYNGDEGDDWTIRWDKADCGYGVMQITDGMRL…
R1I5M4 498-974 None
A0A1H2JKQ5 446-941 None
A0A419I5E6 6-500 None
A0A4S2TXS2 5-453 None
A0A4S2TGW5 152-655 None
U2RXV8 9-424 None
A0A2M9LWX4 372-809 None
D6M5D6 46-592 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.