DPCstruct | MC22106

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)176 ± 14 aa
Standard deviation of domain lengths14.40
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.96
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)23.43
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S1LTF2 202-398 ADWEAKEQAAWDAERAAFTPEALALADHLVCCGLTLTTSSGLACGHGNTYVLAADAPVALWLREALEGAVFSGPEGPWPNWGRTCHA…
A0A1H4I5U5 1-190 MTEATSIELARLRQTGYLYQSTDYVEAFSVPALRLAERLWEDVTGFHNGPYFLPESSPLPGWFLAAVRGFPIRGVEAGWPQFARYWD…
A0A1M6GVS6 208-387 None
A0A4R1F7L4 19-171 None
A0A4Y4B8Q1 24-208 None
A0A851HM77 23-200 None
A0A5N5V6C5 142-303 None
A0A7K2V9Z1 86-270 None
A0A318RVA0 39-196 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.