DPCstruct | MC22104

Metacluster Properties and Pfam Annotations

Number of structural domains164
Mean domain length (aa)137 ± 21 aa
Standard deviation of domain lengths21.47
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.84
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.14
Pfam Score99.09
Assigned Pfam label(s) CL0633- PF00885

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A433VTJ6 3-121 NPRQLAFIALKAVHRDAYADVALDRVLSQSNLNPNDRRLVTELVYGSVRRMRSLDVLIDRLAKKKSHQQPPDLRTILHIGLYQLCYL…
A0A7X7AEF9 6-136 ARETALMVIFQMDLVKAELQDALDFVLQEFAVQPSAIDYARELASGVWEYRENLDGLIQRESTEWEVSRMAVVDRNILRLAVYEMFI…
A0A7T8XQM2 413-560 None
A0A445C2Z3 57-217 None
I5AUS3 12-169 None
A0A3T0Y5Q5 2-132 None
A0A5N9AXH6 2-133 None
A0A011N4I7 22-179 None
A0A1I5U7U7 3-142 None
C8PI00 4-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.