DPCstruct | MC22101

Metacluster Properties and Pfam Annotations

Number of structural domains2595
Mean domain length (aa)118 ± 21 aa
Standard deviation of domain lengths21.40
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.30
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.68
Pfam Score75.27
Assigned Pfam label(s) CL0020- PF19649- PF21537- PF09329- PF03843

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A6CI35 232-316 None
M7A2V5 326-418 None
A0A2I1M7X5 593-732 None
A0A6N6PXP9 73-227 None
A0A6N6Q4L0 14-139 None
A0A521UGI9 170-290 None
A0A2H5ZMK5 20-137 None
A0A7C2XP05 3-105 None
A0A7Z9Y0T9 110-238 None
A0A2S5TFE1 17-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.