DPCstruct | MC22101

Metacluster Properties and Pfam Annotations

Number of structural domains2595
Mean domain length (aa)118 ± 21 aa
Standard deviation of domain lengths21.40
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.30
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.68
Pfam Score75.27
Assigned Pfam label(s) CL0020- PF19649- PF21537- PF09329- PF03843

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A1UUW3 184-303 None
A0A834EC65 2-175 None
A0A7C3UA67 96-208 None
A0A812THP4 469-566 None
A0A0F8T2R6 129-221 None
D8M4K7 37-152 None
A0A135YRZ8 62-190 None
A0A2A4P9Q6 39-203 None
H0TTG6 15-171 None
A0A517VPM7 9-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.