DPCstruct | MC22101

Metacluster Properties and Pfam Annotations

Number of structural domains2595
Mean domain length (aa)118 ± 21 aa
Standard deviation of domain lengths21.40
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.30
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.68
Pfam Score75.27
Assigned Pfam label(s) CL0020- PF19649- PF21537- PF09329- PF03843

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I6MDW7 41-167 None
A0A839YCZ5 286-390 None
A0A6Q2XR43 376-509 None
I4B536 2-148 None
A0A6S7IV35 22-135 None
A0A1R2BY71 11-128 None
A0A2M9Q9X7 11-103 None
K1GQQ5 51-141 None
A0A7C6X489 5-112 None
A0A022N6Z1 8-91 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.