DPCstruct | MC22101

Metacluster Properties and Pfam Annotations

Number of structural domains2595
Mean domain length (aa)118 ± 21 aa
Standard deviation of domain lengths21.40
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.30
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.68
Pfam Score75.27
Assigned Pfam label(s) CL0020- PF19649- PF21537- PF09329- PF03843

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7G3E6P0 186-308 None
A0A653XVK7 16-158 None
A0A520NE81 470-585 None
A0A353R302 191-300 None
A0A5B9YEI2 1-93 None
A0A6M1CKV2 43-153 None
A0A1D6H273 1-120 None
K8A3U5 3-88 None
A0A4P5W8J4 116-224 None
A0A7J9Q2Q0 245-340 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.