DPCstruct | MC22101

Metacluster Properties and Pfam Annotations

Number of structural domains2595
Mean domain length (aa)118 ± 21 aa
Standard deviation of domain lengths21.40
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.30
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.68
Pfam Score75.27
Assigned Pfam label(s) CL0020- PF19649- PF21537- PF09329- PF03843

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645GK07 52-150 PVTAATIAEVLTKPDSNQDYYMVTGEITSIKDAIYGNLYLKDGDSEIYLYGCYPGYGATGDYRKNLLADKGIKVGDKLTVIATKSSY…
A0A2N6BEU8 12-131 VFAVSLPLTSIAAKEYTPSSQAELTRNMDDFLEKDVSIEGTFLFTGSDFCYQIRKTKINTRDYFCFALGPVNLIRFYLKKNHIQVPE…
A0A2N5YL01 255-354 None
A0A164YC77 461-574 None
A0A164MGT8 4-86 None
A0A6A6LI94 359-449 None
A0A2H6KAD4 10-126 None
A0A164Y9N6 346-454 None
A0A843MDE0 20-115 None
A0A3R6LNY5 121-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.