DPCstruct | MC22095

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)101 ± 13 aa
Standard deviation of domain lengths13.42
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score87.91
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)23.93
Pfam Score100.00
Assigned Pfam label(s) PF19854

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S2LN57 6-104 GRKIGDLTELEVLTEQAIKSRQQGQSYCVIKEVLLEDDQFHSFANDFFNDQPWITEEDGGVNENREVRCIRVINQDTGEKILVNNEG…
A0A316QSI0 9-105 KIRFNSKDPAPDVKPFRLRAVEILDENQWAVFSNRLLDDYDFIAKHSDALCVGSDGVTNALLVLNKQTEEGILVNSEGSSYARYSAY…
A0A6G7ZCE8 82-178 None
A0A6M6I9X3 101-199 None
A0A1Y3RVX3 2-85 None
A0A449BEU3 1-101 None
A0A2P5N167 1-80 None
A0A0S2FHS9 16-91 None
A0A096DA96 4-99 None
A0A510Y1F0 8-134 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.