DPCstruct | MC22077

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)166 ± 23 aa
Standard deviation of domain lengths23.34
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score77.24
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)25.46
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R1EBG3 161-283 PVYECTFGFLGCRFFTAGDEEHWRTHNLSHFHGYAPPRQVECPLCDFGFEDARDGHRAWAARMSHLAAHMRLGQTMDASRPDFRLYQ…
A0A094DWJ8 1-184 MLINISSLPCIFQDILACQHINFDDPDSWSGHVIGHFGPSGPPPHALCIFCDKSFEDDNAATCWNGYLDHINEHFKDGRALDRRPDF…
A0A5M9J6Q0 1-181 None
A0A218Z0K6 101-285 None
A0A6V8H8X6 90-297 None
A0A4Z0Z6E7 476-641 None
A0A0B4GU49 493-657 None
A0A1L7XD50 775-987 None
A0A420YI20 443-609 None
A0A2K0US17 92-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.