DPCstruct | MC22060

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)93 ± 8 aa
Standard deviation of domain lengths7.58
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score92.43
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.95
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)52.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0T275 1-105 MEERYGEKGKAIRIEKVIYTGKEGKSSRGCPIAKWVIRRHNQEEKLLCLVRHRAGHHCQNAVIIILILAWEGIPRTLGDTLYQELTD…
A0A5B7E415 1-92 MGKAIRIEKVTYTGKEGKTESGCPLAKWIIRRSGPEEKTLALVKHRSKHTCSTSWIVIALVAWEGVPLNIADDMYSTMVYKLNKFGT…
A0A6J2Y487 110-201 None
A0A3L7IEU6 52-123 None
K1P567 424-513 None
T1KWD2 35-124 None
A0A482WML7 1-92 None
A0A482WJW3 62-164 None
A0A182TII0 19-110 None
E9H3N0 1-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.